28 May Clinical Evidence Review and Economic Analysis of Donor Organ Perfusion Systems
The NSW Ministry of Health (MoH) wished to determine the merits of publicly funding solid organ perfusion systems for use in organ donation. NSW clinicians believed that the use of the systems would increase the number of donor organs that would be suitable for transplant. To inform its investment decision, the MoH engaged HealthConsult to review the clinical and economic evidence on the use of the perfusion systems.
The project involved the development of a stakeholder discussion paper (that included the Population Intervention Comparator Outcome (PICO) framework), which was used to conduct three clinician workshops, as well as undertaking a systematic literature review and critical appraisal and synthesis of clinical evidence for safety and effectiveness. Due to the limitations in the available evidence, HealthConsult also developed a de novo economic model. This material was presented in a technical report, which was used to again engage clinicians in the consideration of system- as well as patient-level benefits associated with the technology.
The work provided a sound evidence base for the MOH’s decision around investment in the technology, thereby ensuring that the available funding was allocated to maximise benefits.